parp inhibitors 3-ab Search Results


parp inhibitors 3-ab  (Porsolt)
90
Porsolt parp inhibitors 3-ab
Effect of poly(ADP-ribose) polymerase <t>(PARP)</t> <t>inhibitors</t> on immobility time (A) and latency to immobility (B) in the Porsolt swim test. Rats were treated daily for 10 days prior to the swim test with either saline (vehicle i.p.: n=13), 3-aminobenzamide (3-AB) administered at 3 different doses as noted (s.c.; n=8-10), or 5-AIQ (0.3 mg/kg i.p.; n=9). Additional groups of rats were administered 3 injections over 24 hours prior to the swim test with either fluoxetine (10 mg/kg i.p. per injection; n=10; FLX x 3) or 3-AB (40 mg/kg s.c. per injection; n=7; 3-AB x 3). The swim test data were collected 2 h after the final drug or vehicle injection. Asterisks indicate significant differences compared to the vehicle group (* P <.05, ** P <.01). The results of statistical analyses of all other comparisons can be found in Supplemental Table 1.
Parp Inhibitors 3 Ab, supplied by Porsolt, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/parp inhibitors 3-ab/product/Porsolt
Average 90 stars, based on 1 article reviews
parp inhibitors 3-ab - by Bioz Stars, 2026-03
90/100 stars
  Buy from Supplier
parp-inhibitor 3-ab  (Micromass UK Limited)
90
Micromass UK Limited parp-inhibitor 3-ab
Effect of poly(ADP-ribose) polymerase <t>(PARP)</t> <t>inhibitors</t> on immobility time (A) and latency to immobility (B) in the Porsolt swim test. Rats were treated daily for 10 days prior to the swim test with either saline (vehicle i.p.: n=13), 3-aminobenzamide (3-AB) administered at 3 different doses as noted (s.c.; n=8-10), or 5-AIQ (0.3 mg/kg i.p.; n=9). Additional groups of rats were administered 3 injections over 24 hours prior to the swim test with either fluoxetine (10 mg/kg i.p. per injection; n=10; FLX x 3) or 3-AB (40 mg/kg s.c. per injection; n=7; 3-AB x 3). The swim test data were collected 2 h after the final drug or vehicle injection. Asterisks indicate significant differences compared to the vehicle group (* P <.05, ** P <.01). The results of statistical analyses of all other comparisons can be found in Supplemental Table 1.
Parp Inhibitor 3 Ab, supplied by Micromass UK Limited, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/parp-inhibitor 3-ab/product/Micromass UK Limited
Average 90 stars, based on 1 article reviews
parp-inhibitor 3-ab - by Bioz Stars, 2026-03
90/100 stars
  Buy from Supplier

Image Search Results


Effect of poly(ADP-ribose) polymerase (PARP) inhibitors on immobility time (A) and latency to immobility (B) in the Porsolt swim test. Rats were treated daily for 10 days prior to the swim test with either saline (vehicle i.p.: n=13), 3-aminobenzamide (3-AB) administered at 3 different doses as noted (s.c.; n=8-10), or 5-AIQ (0.3 mg/kg i.p.; n=9). Additional groups of rats were administered 3 injections over 24 hours prior to the swim test with either fluoxetine (10 mg/kg i.p. per injection; n=10; FLX x 3) or 3-AB (40 mg/kg s.c. per injection; n=7; 3-AB x 3). The swim test data were collected 2 h after the final drug or vehicle injection. Asterisks indicate significant differences compared to the vehicle group (* P <.05, ** P <.01). The results of statistical analyses of all other comparisons can be found in Supplemental Table 1.

Journal: International Journal of Neuropsychopharmacology

Article Title: Antidepressant-Like Actions of Inhibitors of Poly(ADP-Ribose) Polymerase in Rodent Models

doi: 10.1093/ijnp/pyx068

Figure Lengend Snippet: Effect of poly(ADP-ribose) polymerase (PARP) inhibitors on immobility time (A) and latency to immobility (B) in the Porsolt swim test. Rats were treated daily for 10 days prior to the swim test with either saline (vehicle i.p.: n=13), 3-aminobenzamide (3-AB) administered at 3 different doses as noted (s.c.; n=8-10), or 5-AIQ (0.3 mg/kg i.p.; n=9). Additional groups of rats were administered 3 injections over 24 hours prior to the swim test with either fluoxetine (10 mg/kg i.p. per injection; n=10; FLX x 3) or 3-AB (40 mg/kg s.c. per injection; n=7; 3-AB x 3). The swim test data were collected 2 h after the final drug or vehicle injection. Asterisks indicate significant differences compared to the vehicle group (* P <.05, ** P <.01). The results of statistical analyses of all other comparisons can be found in Supplemental Table 1.

Article Snippet: Two structurally different PARP inhibitors, 3-AB and 5-AIQ, demonstrated antidepressant-like activity in the Porsolt swim test.

Techniques: Saline, Injection